Reaktion #6266

Reaktionsgleichung

rhodanine

benzaldehyde

piperidine

→

desired compound

Ausbeute 66.6%

5-benzylidenerhodanine

Ausbeute 66.6%

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturthe mixture was heated
2. 2
   Temperaturunder reflux for 5 hours
3. 3
   TemperaturAfter cooling
4. 4
   Filtrationthe precipitated crystals were filtered
5. 5
   Waschenwashed with cooled ethanol

Vorschrift

To a solution of 10 g (75.1 mmol) of rhodanine and 7.63 ml (75.1 mmol) of benzaldehyde in 150 ml of ethanol, 0.74 ml (7.5 mmol) of piperidine was added, and the mixture was heated under reflux for 5 hours. After cooling, the precipitated crystals were filtered and washed with cooled ethanol to give 11.07 g of the desired compound (66.6% yield, pale yellow crystals).

Quelle