Reaktion #625983

Reaktionsgleichung

solution

2-Oxa-tricyclo[3.3.1.13,7]decane-1-carboxylic acid

thionyl chloride

→

title compound

2-Oxa-tricyclo[3.3.1.13,7]decane-1-carbonyl chloride

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturto reflux
2. 2
   Einengenconcentrated under reduced pressure
3. 3
   workup.ADDITIONThe residue was diluted with 5 mL of toluene
4. 4
   Einengenconcentrated under reduced pressure three times

Vorschrift

A solution of Example 81B (0.1 g, 0.55 mmol) in 5 mL of thionyl chloride was warmed to reflux and stirred for 2 hours. The mixture was cooled to ambient temperature and concentrated under reduced pressure. The residue was diluted with 5 mL of toluene and concentrated under reduced pressure three times to afford the title compound, which was used without additional purification or characterization.

Quelle