Reaktion #62540

Reaktionsgleichung

Peracetic acid

quinoline

→

Quinoline N-oxide

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeMuch of the acetic acid was removed from the reaction mixture in vacuo
2. 2
   workup.DISSOLUTIONThe resulting residue was dissolved in methylene chloride (50 mL)
3. 3
   Waschenwashed twice with saturated sodium bicarbonate solution
4. 4
   TrocknenAfter drying over MgSO4 the solvent
5. 5
   Sonstigewas evaporated
6. 6
   Sonstigethe residue was triturated with ether
7. 7
   FiltrationThe resulting tan solid was collected by filtration

Vorschrift

Peracetic acid (7.5 mL, 39 mmole, 40%) and quinoline (5 g, 39 mmole) were stirred for 2 hours. Much of the acetic acid was removed from the reaction mixture in vacuo. The resulting residue was dissolved in methylene chloride (50 mL) and washed twice with saturated sodium bicarbonate solution. After drying over MgSO4 the solvent was evaporated and the residue was triturated with ether. The resulting tan solid was collected by filtration. This material was carried on without further characterization.

Quelle