Reaktion #62530

ord-ecd2f98b80d3423c9e2f3a399d300e50

Reaktionsgleichung

Cc1ccc(Cl)c(N)c1Cl
2,6-dichloro-3-methylaniline
Cc1cc(C)nc(S(=O)(=O)F)n1
4,6-dimethyl-2-pyrimidinesulfonyl fluoride
→
Cc1cc(C)nc(S(=O)(=O)Nc2c(Cl)ccc(C)c2Cl)n1
desired product
Cc1cc(C)nc(S(=O)(=O)Nc2c(Cl)ccc(C)c2Cl)n1
N-(2,6-Dichloro-3-methylphenyl)-4,6-dimethyl-2-pyrimidinesulfonamide

Edukte

Cc1ccc(Cl)c(N)c1Cl
2,6-dichloro-3-methylaniline
Cc1cc(C)nc(S(=O)(=O)F)n1
4,6-dimethyl-2-pyrimidinesulfonyl fluoride

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

This material was prepared from 2,6-dichloro-3-methylaniline and 4,6-dimethyl-2-pyrimidinesulfonyl fluoride following the general procedure described in Example 2. The desired product was isolated as a solid, m.p. 234°-235°. NMR (90 MHZ) D6 -Acetone: δ 7.4 (d, 2H), 7.3 (s, 1H), 2.5 (s, 6H) and 2.3 (s, 3H).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04761173uspto-grants-1988_08