Reaktion #62129

ord-09cd0a1e86af4e3b9f3f7aa730036eb6

Reaktionsgleichung

O=C(Cc1ccncc1)c1ccc(OCc2ccc3ccccc3n2)cc1
2-pyridin-4-yl-1-[4-(quinolin-2-ylmethoxy)-phenyl]-ethanone
CON(C)C(=O)c1ccc(OCc2ccc3ccccc3n2)c(F)c1F
2,3-Difluoro-N-methoxy-N-methyl-4-(quinolin-2-ylmethoxy)-benzamide
→
O=C(Cc1ccncc1)c1ccc(OCc2ccc3ccccc3n2)c(F)c1F
title compound
O=C(Cc1ccncc1)c1ccc(OCc2ccc3ccccc3n2)c(F)c1F
1-[2,3-Difluoro-4-(quinolin-2-ylmethoxy)-phenyl]-2-pyridin-4-yl-ethanone

Edukte

O=C(Cc1ccncc1)c1ccc(OCc2ccc3ccccc3n2)cc1
2-pyridin-4-yl-1-[4-(quinolin-2-ylmethoxy)-phenyl]-ethanone
CON(C)C(=O)c1ccc(OCc2ccc3ccccc3n2)c(F)c1F
2,3-Difluoro-N-methoxy-N-methyl-4-(quinolin-2-ylmethoxy)-benzamide

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Following the procedure for the preparation of 2-pyridin-4-yl-1-[4-(quinolin-2-ylmethoxy)-phenyl]-ethanone but substituting 2,3-Difluoro-N-methoxy-N-methyl-4-(quinolin-2-ylmethoxy)-benzamide provided the title compound. MS: (M+H m/z=391.1).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07429665B2uspto-grants-2008_09