Reaktion #621161

Reaktionsgleichung

4-(2-Methoxy-phenyl)-thiazol-2-ylamine

4-methyl-benzoyl chloride

→

N-[4-(2-Methoxy-phenyl)-thiazol-2-yl]-4-methyl-benzamide

Lösungsmittel

pyridine

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigepurified by reverse-phase preparative liquid chromatography (7.32 mg, 0.0226 mmol, 11.3%)

Vorschrift

4-(2-Methoxy-phenyl)-thiazol-2-ylamine (41.3 mg, 0.200 mmol) and 4-methyl-benzoyl chloride (30.9 mg, 0.200 mmol) were dissolved in 1 mL of pyridine. The reaction mixture was stirred at room temperature overnight and then purified by reverse-phase preparative liquid chromatography (7.32 mg, 0.0226 mmol, 11.3%). ESI-MS m/z calc. 324.1. found 325.2 (M+1)+ Retention time 3.75 minutes.

Quelle