Reaktion #620554

Reaktionsgleichung

(1-methyl-1H-indol-3-yl)-oxo-acetic acid

dibenzylamine

→

N,N-Dibenzyl-2-(1-methyl-1H-indol-3-yl)-2-oxo-acetamide

Lösungsmittel

CH3CN

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeYield (70%)

Vorschrift

N,N-Dibenzyl-2-(1-methyl-1H-indol-3-yl)-2-oxo-acetamide was synthesized following scheme II above starting from (1-methyl-1H-indol-3-yl)-oxo-acetic acid and dibenzylamine. Yield (70%). HPLC ret. time 3.70 min, 10-99% CH3CN, 5 min run; 1H NMR (400 MHz, DMSO-d6) δ 8.28 (s, 1H), 8.12 (d, J=7.7 Hz, 1H), 7.61 (d, J=8.1 Hz, 1H), 7.43-7.25 (m, 12H), 4.55 (s, 2H), 4.40 (s, 2H), 3.93 (s, 3H); ESI-MS 383.3 m/z (MH+).

Quelle