Reaktion #620539

Reaktionsgleichung

N-phthaloyl-DL-glutamic anhydride

phenethylamine

→

N-phenethylphthalimide

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe reaction mixture was purified by chromatography on a silica gel column

Vorschrift

With reference to Scheme 3 below, a mixture of N-phthaloyl-DL-glutamic anhydride and phenethylamine was heated in a 177° C. oil bath. The reaction mixture was purified by chromatography on a silica gel column to afford N-phenethylthalidomide (8) and N-phenethylphthalimide (9).

Quelle