Reaktion #619769

Reaktionsgleichung

6-(4-Bromo-phenyl)-4,7-dihydro-1-thia-4,5-diaza-cyclopenta[a]pentalene

bromine

→

2-Bromo-6-(4-bromo-phenyl)-4,7-dihydro-1-thia-4,5-diaza-cyclop enta[a]pentalene

Ausbeute 93.0%

Lösungsmittel

acetic acid

Reaktionsbedingungen

Aufarbeitung

1. 1
   TemperaturThe solution was cooled to room temperature
2. 2
   FiltrationThe resultant precipitate was filtered
3. 3
   Waschenwashed with water

Vorschrift

6-(4-Bromo-phenyl)-4,7-dihydro-1-thia-4,5-diaza-cyclopenta[a]pentalene (0.16 g, 0.5 mmol) was added with a solution of bromine in glacial acetic acid (0.5 mL of a 3 M solution). The reaction mixture was heated at 80° C. for 12 hr. The solution was cooled to room temperature and poured into ice water. The resultant precipitate was filtered, washed with water to provide the corresponding 2-Bromo-6-(4-bromo-phenyl)-4,7-dihydro-1-thia-4,5-diaza-cyclop enta[a]pentalene (0.18 g, 0.47 mmol) as yellow solid in 93% yield.

Quelle