Reaktion #619724

Reaktionsgleichung

5-Benzoyl-5,6-dihydro-cyclopenta[b]thiophen-4-one

hydrazine monohydrate

acetic acid

→

6-Phenyl-4,7-dihydro-1-thia-4,5-diaza-cyclopenta[a]pentalene

Ausbeute 80.0%

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   Einengenconcentrated under reduced pressure
2. 2
   Sonstigeto give a solid which
3. 3
   Sonstigewas recrystallized from ethanol

Vorschrift

5-Benzoyl-5,6-dihydro-cyclopenta[b]thiophen-4-one (2.42 g, 10.0 mmol), hydrazine monohydrate (1.92 mL, 60 mmol), glacial acetic acid (2.7 mL) and ethanol (15 mL) was heated at 100° C. under nitrogen for 4 hr. The mixture was cooled to 25° C. and concentrated under reduced pressure to give a solid which was recrystallized from ethanol to provide the corresponding 6-Phenyl-4,7-dihydro-1-thia-4,5-diaza-cyclopenta[a]pentalene (2.4 g, 8.0 mmol) as white solid in 80% yield.

Quelle