Reaktion #61972

Reaktionsgleichung

4-hydroxybenzaldehyde

1-bromo-3-chloropropane

potassium carbonate

→

title compound

4-(3-Chloro-propoxy)-benzaldehyde

Lösungsmittel

acetone

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturwas heated
2. 2
   Temperaturto reflux for 16 h
3. 3
   FiltrationThe resulting mixture was filtered
4. 4
   Sonstigethe filtrate was evaporated
5. 5
   workup.DISTILLATIONDistillation of the residue (0.5 mm Hg, 220° C.)

Vorschrift

A suspension of 4-hydroxybenzaldehyde (40 g), 1-bromo-3-chloropropane (63 mL), and potassium carbonate (136 g) in acetone (920 mL) was heated to reflux for 16 h. The resulting mixture was filtered, and the filtrate was evaporated. Distillation of the residue (0.5 mm Hg, 220° C.) gave the title compound as a pale yellow oil that crystallized on standing (46 g).

Quelle