Reaktion #619182

Reaktionsgleichung

1,1-dicyclohexyl-3-(5-formyl-thiazol-2-yl)-urea

lithium borohydride

→

desired compound

Ausbeute 97.0%

1,1-Dicyclohexyl-3-(5-hydroxymethyl-thiazol-2-yl)-urea

Ausbeute 97.0%

Lösungsmittel

MeOH

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigePrepared
2. 2
   SonstigePurification without work-up (silica gel, 10% EtOAc and 2% MeOH in CH2Cl2)

Vorschrift

Prepared using 1,1-dicyclohexyl-3-(5-formyl-thiazol-2-yl)-urea (50 mg, 0.15 mmol) and lithium borohydride (95 μL, 2M in THF) in MeOH (1 mL). Purification without work-up (silica gel, 10% EtOAc and 2% MeOH in CH2Cl2) afforded 49 mg (97%) of the desired compound.

Quelle