Reaktion #61771

Reaktionsgleichung

3-chloroperbenzoic acid

1-[2-(4-allyloxy-benzylsulfanyl)-ethyl]-1H-[1,2,3]triazole

→

title compound

Ausbeute 62.2%

1-[2-(4-Allyloxy-phenylmethanesulfinyl)-ethyl]-1H-[1,2,3]triazole

Ausbeute 62.2%

Lösungsmittel

ethyl acetate

dichloromethane

Reaktionsbedingungen

Aufarbeitung

1. 1
   Waschenwashed with sat. NaHCO3-solution, water
2. 2
   Sonstigeevaporated
3. 3
   SonstigeThe residue was purified by chromatography on silica gel (ethyl acetate/methanol 5:1)

Vorschrift

A solution of 1.86 g (8.29 mmol) 77% 3-chloroperbenzoic acid in 40 ml ethyl acetate was added at −30° C. within 20 min. to a solution of 1.90 g (6.90 mmol) 1-[2-(4-allyloxy-benzylsulfanyl)-ethyl]-1H-[1,2,3]triazole in 160 ml dichloromethane and stirred for 1 h. The mixture was allowed to warm to room temperature (r.t.) washed with sat. NaHCO3-solution, water and evaporated. The residue was purified by chromatography on silica gel (ethyl acetate/methanol 5:1) to give 1.25 g of the title compound as white powder.

Quelle