Reaktion #61664

Reaktionsgleichung

potassium hydroxide

2-amino-3-nitro-phenol

iodomethane

→

2-methoxy-6-nitro-phenylamine

Lösungsmittel

DMF

Reaktionsbedingungen

Aufarbeitung

1. 1
   workup.ADDITIONThe reaction mixture is poured onto ice
2. 2
   workup.STIRRINGstirred for one hour
3. 3
   FiltrationThe precipitated product is filtered off
4. 4
   Waschenwashed with water
5. 5
   Sonstigedried

Vorschrift

85% potassium hydroxide solution (11.7 g, 0.179 mol) is added to a solution of 25 g (0.162 mol) 2-amino-3-nitro-phenol in 200 mL DMF. Then 11.1 mL (0.178 mol) iodomethane are added dropwise and the mixture is stirred overnight at ambient temperature. The reaction mixture is poured onto ice and stirred for one hour. The precipitated product is filtered off, washed with water and dried.

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