Reaktion #61463

Reaktionsgleichung

2-morpholin-4-yl-5-nitro-benzoic acid

3-piperazin-1-yl-benzo[d]isothiazole hydrochloride

ethyl acetate

→

title compound

(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-(2-morpholin-4-yl-5-nitro-phenyl) -methanone

Lösungsmittel

acetonitrile

Reaktionsbedingungen

Vorschrift

Prepared in analogy to example 1.1 b) from 2-morpholin-4-yl-5-nitro-benzoic acid (Example 2.1) and 3-piperazin-1-yl-benzo[d]isothiazole hydrochloride (CA=87691-88-1) in acetonitrile. Chromatography (SiO2; ethyl acetate) yields the title compound as a colorless solid.

Quelle