Reaktion #614290

Reaktionsgleichung

7-Ethyl-4b,9b-dihydroxy-4bH-benzo[d]indeno[1,2-b]-furan-10(9bH)-one

THF

acetic acid

pyridine

→

title compound

Ausbeute 88.0%

2-(2-Acetoxy-1,3-dioxo-2,3-dihydro-1H-inden-2-yl)-5-ethylphenyl acetate

Ausbeute 88.0%

Reaktionsbedingungen

Aufarbeitung

1. 1
   ExtraktionAfter the reaction mixture was extracted with dichloromethane
2. 2
   Einengenthe organic layer was concentrated
3. 3
   Sonstigepurified

Vorschrift

7-Ethyl-4b,9b-dihydroxy-4bH-benzo[d]indeno[1,2-b]-furan-10(9bH)-one (2.00 g, 7.0 mmol) was completely dissolved in anhydrous THF (20 ml). This solution was added with anhydrous acetic acid (1.44 ml, 14.1 mmol), pyridine (0.56 ml, 7.0 mmol), and 4-dimethyl aminopyridine (0.2 g), and stirred at room temperature for 12 hrs. After the reaction mixture was extracted with dichloromethane, the organic layer was concentrated and purified using column chromatography (ethylacetate:hexane=1:4) to afford the title compound (2.28 g, 88%).

Quelle