Reaktion #61360

Reaktionsgleichung

4-methyl-3-thiosemicarbazide

acetone

chloroacetone

→

3.4-Dimethyl-2(3H)thiazolone-(1-methylethylidene) hydrazone

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturat reflux for 2 hours
2. 2
   Temperaturto reflux for 7 hours
3. 3
   Einengenwas then concentrated
4. 4
   SonstigeThe resulting crude product was recrystallized from acetone

Vorschrift

21 g (200 mmol) of 4-methyl-3-thiosemicarbazide in 1000 mL of acetone was heated at reflux for 2 hours. To this solution was then added dropwise 20.4 g (220 mmol) of chloroacetone. The reaction mixture was allowed to reflux for 7 hours and was then concentrated. The resulting crude product was recrystallized from acetone. This gave 23 g of an orange-colored powder (63% of the theoretical).

Quelle