Reaktion #60986

ord-cbe02993323f47e199ad3f2ba96f5502

Reaktionsgleichung

CS(=O)(=O)c1ccc(Br)cc1
4-bromophenyl methyl sulfone
CC(C)(C)OC(=O)N1CCNCC1
N-Boc-piperazine
→
CC(C)(C)OC(=O)N1CCN(c2ccc(S(C)(=O)=O)cc2)CC1
title compound
CC(C)(C)OC(=O)N1CCN(c2ccc(S(C)(=O)=O)cc2)CC1
4-(4-Methanesulfonyl-phenyl)-piperazine-1-carboxylic acid tert-butyl ester

Edukte

CS(=O)(=O)c1ccc(Br)cc1
4-bromophenyl methyl sulfone
CC(C)(C)OC(=O)N1CCNCC1
N-Boc-piperazine

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title compound was prepared according to the procedure described for example AX from 4-bromophenyl methyl sulfone and N-Boc-piperazine (31%, white solid, MS (m/e): 241.2(M-Boc, 100%)

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07427612B2uspto-grants-2008_09