Reaktion #6097

ord-b26089eaf91d4f27b4272b0ec41c29a8

Reaktionsgleichung

[K+].[OH-]
potassium hydroxide
N#Cc1cccc(O)c1
3-hydroxybenzonitrile
CN(C)C(=S)Cl
dimethylthiocarbamoyl chloride
→
CN(C)C(=S)Oc1cccc(C#N)c1
expected product
CN(C)C(=S)Oc1cccc(C#N)c1
O-3-cyanophenyl dimethylthiocarbamate

Edukte

[K+].[OH-]
potassium hydroxide
—
XI
N#Cc1cccc(O)c1
3-hydroxybenzonitrile
CN(C)C(=S)Cl
dimethylthiocarbamoyl chloride

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

If the procedure described in Preparation XI is followed starting from 15 g (126.10-3 mol) of 3-hydroxybenzonitrile, 17.9 g (145.10-3 mol) of dimethylthiocarbamoyl chloride and 7.4 g (132.10-3 mol) of potassium hydroxide, 29 g (quantitative yield) of the expected product are obtained.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05246961uspto-grants-1993_09