Reaktion #60760

ord-748271b77f2241a78a61dcc32a565b30

Reaktionsgleichung

CC(C)(C)N=C=O
t-butyl isocyanate
[N-]=C=O
isocyanate
NC1=c2ccoc2=NCN1c1cccc(N)c1
4-Amino-3-(3-aminophenyl)furo[2,3-d]pyrimidine
→
CC(C)(C)NC(=O)Nc1cccc(N2CN=c3occc3=C2N)c1
4-Amino-3-(3-((tert-butyl)aminocarbonylamino)phenyl)furo[2,3-d]pyrimidine

Edukte

—
diamine
CC(C)(C)N=C=O
t-butyl isocyanate
[N-]=C=O
isocyanate
NC1=c2ccoc2=NCN1c1cccc(N)c1
4-Amino-3-(3-aminophenyl)furo[2,3-d]pyrimidine

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigeThe compound was prepared

Vorschrift

The compound was prepared following the procedure described in Example 232(b), using t-butyl isocyanate as the isocyanate of choice, and 4-Amino-3-(3-aminophenyl)furo[2,3-d]pyrimidine (10) as the diamine of choice. MS(ES) m/e 326 [M+H]+.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07427623B2uspto-grants-2008_09