Reaktion #60737

Reaktionsgleichung

4-hydroximino-4-phenylbutyric acid

1-isopropylpiperazine dihydrochloride

→

1-(4-Isopropylpiperazin-1-yl)-4-phenylbutane-1,4-dione 4-oxime

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeafforded
2. 2
   Sonstigeafter purification (SiO2: 10% isopropylamine in EtOAc), 730 mg (89%) of the title compound

Vorschrift

Using coupling method A, 4-hydroximino-4-phenylbutyric acid (500 mg, 2.6 mmol) and 1-isopropylpiperazine dihydrochloride (521 mg, 2.6 mmol) afforded, after purification (SiO2: 10% isopropylamine in EtOAc), 730 mg (89%) of the title compound.

Quelle