Reaktion #60684

Reaktionsgleichung

4-[2-amino-2-(4-fluorophenyl)-ethoxymethyl]piperidine-1-carboxylic acid tert-butyl ester

3-chloroindole-6-carboxylic acid

→

title compound

Ausbeute 100.6%

4-{2-[(3-Chloro-1H-indole-6-carbonyl)amino]-2-(4-fluoro-phenyl)ethoxymethyl}piperidine-1-carboxylic acid tert-butyl ester

Ausbeute 100.6%

Reaktionsbedingungen

Vorschrift

Using coupling method A, 4-[2-amino-2-(4-fluorophenyl)-ethoxymethyl]piperidine-1-carboxylic acid tert-butyl ester (1.1 g, 3.0 mmol) and 3-chloroindole-6-carboxylic acid (653 mg, 3.3 mmol) afforded 1.6 g (100%) of the title compound as a crude residue, which was used without further purification.

Quelle