Reaktion #60650

Reaktionsgleichung

tert-butyl 2-(2-azidoethoxy)ethylcarbamate

→

tert-butyl 2-(2-aminoethoxy)ethylcarbamate

Ausbeute 84.7%

Lösungsmittel

MeOH

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationThe solution was then filtered through a Celite pad
2. 2
   Einengenconcentrated

Vorschrift

A solution of tert-butyl 2-(2-azidoethoxy)ethylcarbamate (47.0 g, 0.204 mol) in MeOH was treated with 4 g of 10% Pd on carbon and shaken under H2 (3 Kg/cm2) for 24 hours. The solution was then filtered through a Celite pad and concentrated to give 35.3 g of crude tert-butyl 2-(2-aminoethoxy)ethylcarbamate as a colorless liquid that was used without further purification.

Quelle