Reaktion #60574

ord-330a54dcbc11486699277462ebd22a21

Reaktionsgleichung

C=CS(=O)(=O)C=C.CC(C)C[C@H](NC(=O)[C@@H](N)CC(N)=O)C(=O)O
compound ( i )
C=CS(=O)(=O)C=C.CC(C)C[C@H](NC(=O)[C@@H](N)CC(N)=O)C(=O)O
Asn-Leu vinylsulfone
NC(=O)C[C@H](N)C(=O)O.N[C@@H](CCC(=O)O)C(=O)O
Glu asparagine
→
C=CS(=O)(=O)C=C.CC(C)C[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)CCC(=O)O)C(=O)O
Glu-Asn-Leu vinylsulfone

Edukte

C=CS(=O)(=O)C=C.CC(C)C[C@H](NC(=O)[C@@H](N)CC(N)=O)C(=O)O
compound ( i )
C=CS(=O)(=O)C=C.CC(C)C[C@H](NC(=O)[C@@H](N)CC(N)=O)C(=O)O
Asn-Leu vinylsulfone
NC(=O)C[C@H](N)C(=O)O.N[C@@H](CCC(=O)O)C(=O)O
Glu asparagine

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigeThis compound is synthesized

Vorschrift

This compound is synthesized as described above for compound (i), except that Glu-asparagine is used in step (g).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07427591B2uspto-grants-2008_09