Reaktion #6027

Reaktionsgleichung

product

methyl 4-tert-butyldimethylsilyloxy-3,5-di(2-propen-1-yl)benzoate

hydrogen

→

title compound

Ausbeute 90.0%

methyl 4-tert-butyldimethylsilyloxy-3,5-dipropylbenzoate

Ausbeute 90.0%

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationUpon completion of reduction, the mixture was filtered through Celite
2. 2
   Waschenthe filter cake was washed with methanol and dichloromethane
3. 3
   SonstigeRemoval of solvents

Vorschrift

A solution of 5.0 g (14.45 mmol) of the product of Step C in 250 mL ethanol containing 5% Rh/C (0.25 g) was shaken under a 40 psi pressure of hydrogen. Upon completion of reduction, the mixture was filtered through Celite, the filter cake was washed with methanol and dichloromethane. Removal of solvents afforded 4.55 g (90%) of the title compound.

Quelle