Reaktion #6025

ord-3170c5d6164841af935791c864839bf7

Reaktionsgleichung

C=CCOc1ccc(C(=O)OC)cc1CC=C
product
C=CCOc1ccc(C(=O)OC)cc1CC=C
methyl 3-(2-propen-1-yl)-4-(2-propen-1-yloxy)benzoate
Clc1ccccc1Cl
1,2-dichlorobenzene
CCOC(C)=O
ethyl acetate
→
C=CCc1cc(C(=O)OC)cc(CC=C)c1O
title compound
Ausbeute 97.0%
C=CCc1cc(C(=O)OC)cc(CC=C)c1O
methyl 4-hydroxy-3,5-di(2-propen-1-yl)benzoate
Ausbeute 97.0%

Edukte

C=CCOc1ccc(C(=O)OC)cc1CC=C
product
C=CCOc1ccc(C(=O)OC)cc1CC=C
methyl 3-(2-propen-1-yl)-4-(2-propen-1-yloxy)benzoate
Clc1ccccc1Cl
1,2-dichlorobenzene
CCOC(C)=O
ethyl acetate

Reagenzien

Keine

Lösungsmittel

CCCCCC
hexane
CCCCCC
hexane

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The product of Step A (3.2 g, 13.8 mmol) was refluxed in 1,2-dichlorobenzene for 3 days in the presence of a catalytic amount of BHT (10 mg). Flash column chromatography of the mixture using hexane and then 10% and 20% ethyl acetate in hexane afforded 3.1 g (97%) of the title compound.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05246944uspto-grants-1993_09