Reaktion #60199

ord-563adb478c9f459cb0ea45d4f334cec9

Reaktionsgleichung

O=C(Cc1cc[nH]n1)c1ccc(Cl)cc1Cl
1-(2,4-dichlorophenyl)-2-pyrazolylethan-1-one
Cc1c[nH]cn1
4-methylimidazole
Cc1c[nH]c(CC(=O)c2ccc(Cl)cc2Cl)n1
1-(2,4-Dichlorophenyl)-2-(4-methylimidazolyl)ethan-1-one

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigeThe crude residue was purified on silica gel (5% MeOH/CH2Cl2)
  2. 2
    Sonstigeto yield a light yellow solid

Vorschrift

Made using the same procedure as for 1-(2,4-dichlorophenyl)-2-pyrazolylethan-1-one except that 4-methylimidazole (3.7 g, 44.8 mmol) was used in place of pyrazole. The crude residue was purified on silica gel (5% MeOH/CH2Cl2) to yield a light yellow solid.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07425557B2uspto-grants-2008_09