Reaktion #6011

Reaktionsgleichung

acetyl chloride

aluminum chloride

dimethylformamide

benzoselenazolinone

→

6-Acetylbenzoselenazolinone

Reaktionsbedingungen

Aufarbeitung

1. 1
   TemperaturAfter cooling
2. 2
   workup.STIRRINGthe mixture is homogenized
3. 3
   TemperaturIt is heated to 70°-80° C. on an oil bath
4. 4
   workup.STIRRINGwith stirring
5. 5
   Temperaturheating
6. 6
   Temperaturis maintained at a temperature of 80°-90° C. for a time T of approximately 4 h 30 min
7. 7
   Sonstigeon crushed ice
8. 8
   Sonstigedried
9. 9
   Waschenwashed with boiling cyclohexane
10. 10
    Sonstigerecrystallized in toluene

Vorschrift

12 grams (0.09 mol) of aluminum chloride are introduced into a ground-necked flask. 3.1 cm3 (0.04 mol) of dimethylformamide are added dropwise with stirring. After cooling, two grams (0.01 mol) of benzoselenazolinone are added and the mixture is homogenized. It is heated to 70°-80° C. on an oil bath with stirring, and 0.01 to 0.012 mol of acetyl chloride is then added. heating is maintained at a temperature of 80°-90° C. for a time T of approximately 4 h 30 min. The mixture is hydrolyzed on crushed ice. The product is drained, dried, and washed with boiling cyclohexane and recrystallized in toluene.

Quelle