Reaktion #600181

ord-8f2aa30af14448d1b77acf85130a32af

Reaktionsgleichung

CNC(=O)c1cc(Br)ccc1OC(F)F
5-bromo-2-difluoromethoxy-N-methyl-benzamide
CC1(C)OB(c2ccc(OC(F)F)c(C(N)=O)c2)OC1(C)C
2-Difluoromethoxy-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzamide
→
CNC(=O)c1cc(B2OC(C)(C)C(C)(C)O2)ccc1OC(F)F
2-Difluoromethoxy-N-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzamide

Edukte

CNC(=O)c1cc(Br)ccc1OC(F)F
5-bromo-2-difluoromethoxy-N-methyl-benzamide
CC1(C)OB(c2ccc(OC(F)F)c(C(N)=O)c2)OC1(C)C
2-Difluoromethoxy-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzamide

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

2-Difluoromethoxy-N-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzamide was prepared in a similar way as 2-Difluoromethoxy-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzamide using 5-bromo-2-difluoromethoxy-N-methyl-benzamide as the starting material.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US09102670B2uspto-grants-2015_08