Reaktion #599498

ord-40868fe9b6cf4eda98934e729d8d35cf

Reaktionsgleichung

O=C(O)c1ccccc1Cl
2-chlorobenzoic acid
NCC(CC1(C(F)(F)F)CC1)c1cnc(C(F)(F)F)nc1
3-(1-(trifluoromethyl)cyclopropyl)-2-(2-(trifluoromethyl)pyrimidin-5-yl)propan-1-amine
→
O=C(NCC(CC1(C(F)(F)F)CC1)c1cnc(C(F)(F)F)nc1)c1ccccc1Cl
2-chloro-N-(3-(1-(trifluoromethyl)cyclopropyl)-2-(2-(trifluoromethyl)pyrimidin-5-yl)propyl)benzamide

Edukte

O=C(O)c1ccccc1Cl
2-chlorobenzoic acid
NCC(CC1(C(F)(F)F)CC1)c1cnc(C(F)(F)F)nc1
3-(1-(trifluoromethyl)cyclopropyl)-2-(2-(trifluoromethyl)pyrimidin-5-yl)propan-1-amine

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

From 2-chlorobenzoic acid and 3-(1-(trifluoromethyl)cyclopropyl)-2-(2-(trifluoromethyl)pyrimidin-5-yl)propan-1-amine. LCMS (MH+): m/z=452.0, tR (minutes, Method F)=3.03

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US09102591B2uspto-grants-2015_08