Reaktion #599490

ord-fae753aff69843f7857e3b75daa2243c

Reaktionsgleichung

O=C(O)c1cccc(Cl)c1Cl
2,3-dichlorobenzoic acid
CC(CN)(CC1CC1)c1cnc(C(F)(F)F)nc1
3-cyclopropyl-2-methyl-2-(2-(trifluoromethyl)pyrimidin-5-yl)propan-1-amine
→
CC(CNC(=O)c1cccc(Cl)c1Cl)(CC1CC1)c1cnc(C(F)(F)F)nc1
2,3-dichloro-N-(3-cyclopropyl-2-methyl-2-(2-(trifluoromethyl)pyrimidin-5-yl)propyl)benzamide

Edukte

O=C(O)c1cccc(Cl)c1Cl
2,3-dichlorobenzoic acid
CC(CN)(CC1CC1)c1cnc(C(F)(F)F)nc1
3-cyclopropyl-2-methyl-2-(2-(trifluoromethyl)pyrimidin-5-yl)propan-1-amine

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

From 2,3-dichlorobenzoic acid and 3-cyclopropyl-2-methyl-2-(2-(trifluoromethyl)pyrimidin-5-yl)propan-1-amine. LCMS (MH+): m/z=432.1, tR (minutes, Method G)=2.58

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US09102591B2uspto-grants-2015_08