Reaktion #59949

Reaktionsgleichung

2-((benzyloxy)methyl)-5,5-difluoro-1,3-dioxane

hydrogen

→

title compound

Ausbeute 97.4%

(5,5-difluoro-1,3-dioxan-2-yl)methanol

Ausbeute 97.4%

Lösungsmittel

ethyl acetate

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationThe reaction mixture was filtrated
2. 2
   Einengenthe filtrate was concentrated under reduced pressure

Vorschrift

A mixture of 2-((benzyloxy)methyl)-5,5-difluoro-1,3-dioxane (930 mg, 3.81 mmol), 20% palladium hydroxide (353 mg), and ethyl acetate (30 ml) was stirred in a hydrogen atmosphere at room temperature for 4 hours and 25 minutes. The reaction mixture was filtrated and the filtrate was concentrated under reduced pressure to obtain the title compound (572 mg, 97.4%) as a colorless oil.

Quelle