Reaktion #599484

ord-ad81bc8a7caf42c59ba92808ed77f9d1

Reaktionsgleichung

O=C(O)c1cccc(Cl)c1Cl
2,3-dichlorobenzoic acid
Cc1ncc(C(CN)c2ccncc2)cn1
2-(2-methylpyrimidin-5-yl)-2-(pyridin-4-yl)ethanamine
→
Cc1ncc(C(CNC(=O)c2cccc(Cl)c2Cl)c2ccncc2)cn1
2,3-dichloro-N-(2-(2-methylpyrimidin-5-yl)-2-(pyridin-4-yl)ethyl)benzamide

Edukte

O=C(O)c1cccc(Cl)c1Cl
2,3-dichlorobenzoic acid
Cc1ncc(C(CN)c2ccncc2)cn1
2-(2-methylpyrimidin-5-yl)-2-(pyridin-4-yl)ethanamine

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

From 2,3-dichlorobenzoic acid and 2-(2-methylpyrimidin-5-yl)-2-(pyridin-4-yl)ethanamine. LCMS (MH+): m/z=387.1, tR (minutes, Method F)=1.56

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US09102591B2uspto-grants-2015_08