Reaktion #599452

ord-ccef48bbc136488fbe2d1bf3e11e4ea0

Reaktionsgleichung

O=C(O)c1cccc(Cl)c1Cl
2,3-dichlorobenzoic acid
NCC(CC1CC1)c1cnc(C(F)(F)F)nc1
2-(2-trifluoromethyl-pyrimidin-5-yl)-3-cyclopropyl-propylamine
→
O=C(NCC(CC1CC1)c1cnc(C(F)(F)F)nc1)c1cccc(Cl)c1Cl
2,3-Dichloro-N-[3-cyclopropyl-2-[2-(trifluoromethyl)pyrimidin-5-yl]propyl]benzamide

Edukte

O=C(O)c1cccc(Cl)c1Cl
2,3-dichlorobenzoic acid
NCC(CC1CC1)c1cnc(C(F)(F)F)nc1
2-(2-trifluoromethyl-pyrimidin-5-yl)-3-cyclopropyl-propylamine

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

From 2,3-dichlorobenzoic acid and 2-(2-trifluoromethyl-pyrimidin-5-yl)-3-cyclopropyl-propylamine. LCMS (MH+): m/z=418.1, tR (minutes, Method G)=2.55

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US09102591B2uspto-grants-2015_08