Reaktion #599448

ord-b9d24cb6c6cc49959ea7ed142a9b5d70

Reaktionsgleichung

O=C(O)c1ccccc1Cl
2-chlorobenzoic acid
NCC(CC1(C(F)(F)F)CC1)c1ccc(C(F)(F)F)nc1
3-(1-trifluoromethyl-cyclopropyl)-2-(6-trifluoromethyl-pyridin-3-yl)-propylamine
→
O=C(NCC(CC1(C(F)(F)F)CC1)c1ccc(C(F)(F)F)nc1)c1ccccc1Cl
2-Chloro-N-[3-[1-(trifluoromethyl)cyclopropyl]-2-[6-(trifluoromethyl)-3-pyridyl]propyl]benzamide

Edukte

O=C(O)c1ccccc1Cl
2-chlorobenzoic acid
NCC(CC1(C(F)(F)F)CC1)c1ccc(C(F)(F)F)nc1
3-(1-trifluoromethyl-cyclopropyl)-2-(6-trifluoromethyl-pyridin-3-yl)-propylamine

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

From 2-chlorobenzoic acid and 3-(1-trifluoromethyl-cyclopropyl)-2-(6-trifluoromethyl-pyridin-3-yl)-propylamine. LCMS (MH+): m/z=451.1, tR (minutes, Method G)=2.58

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US09102591B2uspto-grants-2015_08