Reaktion #599447

ord-e8e605f52566466a87314cf125ee50b6

Reaktionsgleichung

O=C(O)c1cccc(Cl)c1Cl
2,3-dichlorobenzoic acid
Cc1ncc(C(CN)CC2CC2)cn1
2-(2-methyl-pyrimidin-5-yl)-3-cyclopropyl-propylamine
→
Cc1ncc(C(CNC(=O)c2cccc(Cl)c2Cl)CC2CC2)cn1
2,3-Dichloro-N-[3-cyclopropyl-2-(2-methylpyrimidin-5-yl)propyl]benzamide

Edukte

O=C(O)c1cccc(Cl)c1Cl
2,3-dichlorobenzoic acid
Cc1ncc(C(CN)CC2CC2)cn1
2-(2-methyl-pyrimidin-5-yl)-3-cyclopropyl-propylamine

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

From 2,3-dichlorobenzoic acid and 2-(2-methyl-pyrimidin-5-yl)-3-cyclopropyl-propylamine. LCMS (MH+): m/z=364.1, tR (minutes, Method F)=2.52

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US09102591B2uspto-grants-2015_08