Reaktion #59939

Reaktionsgleichung

( 3h )

2-(((3-methyl-4-(2-(2-propyl-1,3-dioxolan-2-yl)ethoxy)pyridin-2-yl)methyl)sulfinyl)-1H-benzimidazole sodium salt

4-chloro-2,3-dimethylpyridine 1-oxide

(2-ethyl-1,3-dioxan-2-yl)methanol

→

title compound

Ausbeute 9.6%

2-(((4-((2-ethyl-1,3-dioxan-2-yl)methoxy)-3-methylpyridin-2-yl)methyl)sulfinyl)-1H-benzimidazole sodium salt

Ausbeute 9.6%

Reaktionsbedingungen

Vorschrift

The same procedure as in the steps (3c) to (3h) of Example 3 was repeated using 4-chloro-2,3-dimethylpyridine 1-oxide and (2-ethyl-1,3-dioxan-2-yl)methanol to obtain the title compound (305 mg, 6 steps: 9.6%) as a solid.

Quelle