Reaktion #59929

Reaktionsgleichung

( 24f )

2-(((3-methyl-4-((1-methyl-2,6,7-trioxabicyclo[2.2.2]oct-4-yl)methoxy)pyridin-2-yl)methyl)sulfinyl)-1H-benzimidazole sodium salt

(1-cyclopropyl-2,6,7-trioxabicyclo[2.2.2]oct-4-yl)methanol

→

title compound

Ausbeute 3.2%

2-(((4-((1-cyclopropyl-2,6,7-trioxabicyclo[2.2.2]oct-4-yl)methoxy)-3-methylpyridin-2-yl)methyl)sulfinyl)-1H-benzimidazole sodium salt

Ausbeute 3.2%

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeobtained in the step (37c) above

Vorschrift

The same procedure as in the steps (24b) to (24f) of Example 24 was repeated using (1-cyclopropyl-2,6,7-trioxabicyclo[2.2.2]oct-4-yl)methanol obtained in the step (37c) above to obtain the title compound (147 mg, total yield: 3.2%) as a light yellow solid.

Quelle