Reaktion #5982

Reaktionsgleichung

methyl 1-acetylamino-2-chloro6,7,8,9-tetrahydrodibenzofuran-4-carboxylate

→

methyl 1-acetylamino-2-chlorodibenzofuran-4-carboxylate

Reaktionsbedingungen

Aufarbeitung

1. 1
   ExtraktionThe cooled residue is extracted with toluene
2. 2
   Sonstigethe solvent evaporated to dryness
3. 3
   SonstigeThe residue is crystallized from ethyl acetate/hexane

Vorschrift

A mixture of 1 g methyl 1-acetylamino-2-chloro6,7,8,9-tetrahydrodibenzofuran-4-carboxylate and 0.5 g of 5% palladium-charcoal is heated under nitrogen at 230° C. for 5 hours. The cooled residue is extracted with toluene and the solvent evaporated to dryness. The residue is crystallized from ethyl acetate/hexane to give methyl 1-acetylamino-2-chlorodibenzofuran-4-carboxylate.

Quelle