Reaktion #597422

Reaktionsgleichung

5-methyl-1,3-cyclohexanedione

bromine

→

2-bromo-5-methylcyclohexane-1,3-dione

Lösungsmittel

acetic acid

Reaktionsbedingungen

Aufarbeitung

1. 1
   Filtrationthe reaction mixture was filtered
2. 2
   workup.WAITThe solid was left under high vacuum overnight
3. 3
   Sonstigeused in the subsequent step without further purification

Vorschrift

To a solution of 5-methyl-1,3-cyclohexanedione (23) (45.4 g, 360 mmol) in acetic acid (540 mL) was added bromine (19.4 mL, 378 mmol) over 5 min. After 30 min of stirring (with mechanical stirrer), the reaction mixture was filtered. The solid was left under high vacuum overnight and used in the subsequent step without further purification.

Quelle