Reaktion #59742

Reaktionsgleichung

Intermediate 6

6,2′-Dimethyl-4′-(5-methyl-[1,2,4]oxadiazol-3-yl)-biphenyl-3-carboxylic acid (3-morpholin-4-yl-phenyl)amide

2-(4iodophenyl)-5-methyl-[1,3,4]oxadiazole

2-(4-iodophenyl)-5-methyl-[1,3,4]oxadiazole

Intermediate 15

2-(4-iodophenyl)-5-methyl-[1,3,4]oxadiazole

propan-2-ol

4-methyl-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzamide

6,2′-Dimethyl-4′-(5-methyl-[1,2,4]oxadiazol-3-yl)-biphenyl-3-carboxylic acid (3-morpholin-4-yl-phenyl)amide

→

6-Methyl-4′-(5-methyl-[1,3,4]oxadiazol-2-yl)-biphenyl-3-carboxylic acid (3-methoxy-phenyl)-amide

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeExample 37 was prepared

Vorschrift

Example 37 was prepared using 2-(4iodophenyl)-5-methyl-[1,3,4]oxadiazole (Intermediate 15) and N-3-methoxy-phenyl)-4-methyl-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzamide (Intermediate 6) with propan-2-ol as the solvent.

Quelle