Reaktion #59406

Reaktionsgleichung

(R)-3-t-butyloxycarbonylamino-1-methyl-3,4-dihydrocarbostyril

hydrogen chloride

→

(R)-3-amino-1-methyl-3,4-dihydrocarbostyril hydrochloride

Lösungsmittel

1,4-dioxane

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeAfter 1 h the solvent was evaporated under vacuum
2. 2
   Sonstigeevaporated under vacuum

Vorschrift

(R)-3-t-butyloxycarbonylamino-1-methyl-3,4-dihydrocarbostyril (20 mg) was dissolved in 4 M hydrogen chloride in 1,4-dioxane solution (5 mL) at room temperature. After 1 h the solvent was evaporated under vacuum, and the residue was twice taken up in toluene (5 mL) and evaporated under vacuum to provide (R)-3-amino-1-methyl-3,4-dihydrocarbostyril hydrochloride (25 mg).

Quelle