Reaktion #591

Reaktionsgleichung

CN1CC(c2ccccc2)Oc2nc

Cc1nccn1-c1ccc(N)cc1

→

Cc1nccn1-c1ccc(Nc2cc

Ausbeute 42.3%

Lösungsmittel

COCCOC

Reaktionsbedingungen

Vorschrift

were placed in a microwave vial equipped with a stirring bar. The vial was capped and flushed with argon. DME (2 mL) was added via a syringe and the mixture was heated to 100°C in a microwave apparatus for 1h. The reaction mixture was filtered, the solvent was evaporated and the residue was purified by HPLC to give 53 mg (42 % yield) of the product as a solid.

Quelle