Reaktion #59024

Reaktionsgleichung

hydrochloric acid

Lithium hydroxide monohydrate

4-ethoxycarbonyl-2-methoxyphenylboronic acid

water

→

title compound

Ausbeute 81.7%

4-Carboxy-2-methoxyphenylboronic acid

Ausbeute 81.7%

Lösungsmittel

1,4-dioxane

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigethe solvent was evaporated under reduced pressure
2. 2
   WaschenThe residue was washed with water

Vorschrift

Lithium hydroxide monohydrate (0.092 g) was added to a mixture of 4-ethoxycarbonyl-2-methoxyphenylboronic acid (0.049 g), water (1 mL) and 1,4-dioxane (1 mL), and the mixture was stirred at room temperature overnight. 2 mol/L hydrochloric acid (1.09 mL) was added to the reaction mixture, and the solvent was evaporated under reduced pressure. The residue was washed with water to afford the title compound (0.035 g).

Quelle