Reaktion #59018

Reaktionsgleichung

methyl 4-benzyloxy-2-methoxybenzoate

tetrahydrofuran

→

title compound

Ausbeute 98.0%

Methyl 4-hydroxy-2-methoxybenzoate

Ausbeute 98.0%

Lösungsmittel

methanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe catalyst was removed by filtration
2. 2
   Einengenthe filtrate was concentrated in vacuo

Vorschrift

To a solution of methyl 4-benzyloxy-2-methoxybenzoate (3.08 g) in methanol (5 mL)/tetrahydrofuran (7.5 mL) was added 10% palladium-carbon (0.3 g) at room temperature under an atmosphere of argon, and the mixture was stirred at that temperature for 2 hrs under an atmosphere of hydrogen. The catalyst was removed by filtration, and the filtrate was concentrated in vacuo to afford the title compound (2.02 g).

Quelle