Reaktion #590145

ord-ab7824f87fc8483caed02b6564f89f04

Reaktionsgleichung

O=C(Cl)c1ccccc1C(F)(F)F
2-(Trifluoromethyl)benzoyl chloride
CN
methylamine
→
CNC(=O)c1ccccc1C(F)(F)F
N-methyl-2-(trifluoromethyl)benzamide

Edukte

O=C(Cl)c1ccccc1C(F)(F)F
2-(Trifluoromethyl)benzoyl chloride
CN
methylamine

Reagenzien

Keine

Lösungsmittel

ClC(Cl)Cl
chloroform

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

2-(Trifluoromethyl)benzoyl chloride and methylamine (2M, THF solution) were reacted in chloroform at room temperature to obtain N-methyl-2-(trifluoromethyl)benzamide.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07776897B2uspto-grants-2010_08