Reaktion #5886

Reaktionsgleichung

nitro

2-tert-butyl-5-(4-methylpiperazin-1-yl)-6-nitrobenzothiazole

→

6-amino-2-tert-butyl-5-(4-methylpiperazin-1-yl)benzothiazole

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationThe solution is filtered

Vorschrift

A solution of 86 g of the above nitro compound in 150 ml of ethanol is hydrogenated in presence of 30 g of Raney nickel at 45°. The solution is filtered to give 6-amino-2-tert-butyl-5-(4-methylpiperazin-1-yl)benzothiazole, melting at 130° C.

Quelle