Reaktion #587225

Reaktionsgleichung

chlorotrimethylsilane

1-butanol

1-methylimidazole

→

1-trimethylsilyloxybutane

Ausbeute 89.4%

Reaktionsbedingungen

Aufarbeitung

1. 1
   workup.STIRRINGThe reaction mixture was stirred for another 15 minutes at 0-5° C. and for 15 minutes at 20° C.
2. 2
   Sonstigeresulting in the formation of a liquid two-phase mixture
3. 3
   SonstigeThe upper phase was separated off

Vorschrift

4.40 g (40.5 mmol) of chlorotrimethylsilane were added dropwise to a solution of 3.00 g (40.5 mmol) of 1-butanol and 11.1 g (135 mmol) of 1-methylimidazole while stirring at 0° C. The reaction mixture was stirred for another 15 minutes at 0-5° C. and for 15 minutes at 20° C., resulting in the formation of a liquid two-phase mixture. The upper phase was separated off to give 5.30 g (theory: 5.93 g) of 1-trimethylsilyloxybutane as a colorless oil having a purity of 90% (GC).

Quelle