Reaktion #585687

Reaktionsgleichung

4,5-dichlorophenylenediamine

3-oxo-3-(3-pyridin-3-yl-phenyl)-propionic acid tert-butyl ester

→

title compound

7,8-Dichloro-4-(3-pyridin-3-yl-phenyl)-1,3-dihydro-benzo[b][1,4]diazepin-2-one

Lösungsmittel

xylene

Reaktionsbedingungen

Vorschrift

The title compound was prepared from 4,5-dichlorophenylenediamine (172 mg, 0.97 mmol) and 3-oxo-3-(3-pyridin-3-yl-phenyl)-propionic acid tert-butyl ester (Example K1) (289 mg, 0.97 mmol) by refluxing in xylene according to the general procedure M. Obtained as an off-white solid (310 mg).

Quelle