Reaktion #58556

Reaktionsgleichung

product

1-Benzyl-4-thiophen-2-yl-piperidine-3-carboxylic acid ethyl ester

→

subtitle compound

Ausbeute 100.0%

1-Benzyl-4-thiophen-2-yl-piperidine-3-carboxylic acid

Ausbeute 100.0%

Lösungsmittel

HCl

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeNext, the reaction was evaporated to dryness
2. 2
   Sonstigeazeotroped with toluene (2×50 ml)

Vorschrift

The product from step b) (6.83 g, 20.7 mmol) was treated with 4 M HCl (400 ml) at 100° C. for 16 hours. Next, the reaction was evaporated to dryness, azeotroped with toluene (2×50 ml) and placed on the high vacuum to give the subtitle compound (7 g, 100%). MS calculated for C17H19NO2S−H 300, observed 300.

Quelle